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5–4 ?mol/L vary,[156][157] the focus of serotonin in synaptic vesicles was calculated at 270 mM.[182] pursuing vesicular release, the resulting concentration of serotonin from the synaptic cleft, to which serotonin receptors are exposed, is approximated to get about 300 ?mol/L. Thus, whilst in vitro receptor binding affinities, efficacies, and

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